{"id":2926,"date":"2025-01-27T11:22:07","date_gmt":"2025-01-27T14:22:07","guid":{"rendered":"https:\/\/www.carloschagas.org.br\/?post_type=publicacoes&p=2926"},"modified":"2025-01-27T11:23:29","modified_gmt":"2025-01-27T14:23:29","slug":"efficacy-of-standard-triple-therapy-for-helicobacter-pylori-eradication-and-early-postoperative-complications-in-patients-undergoing-roux-en-y-gastric-bypass","status":"publish","type":"publicacoes","link":"https:\/\/www.carloschagas.org.br\/en\/publicacoes\/portugues-do-brasil-efficacy-of-standard-triple-therapy-for-helicobacter-pylori-eradication-and-early-postoperative-complications-in-patients-undergoing-roux-en-y-gastric-bypass\/","title":{"rendered":"(Portugu\u00eas do Brasil) Efficacy of Standard Triple Therapy for Helicobacter pylori Eradication and Early Postoperative Complications in Patients Undergoing Roux-en-Y Gastric Bypass"},"content":{"rendered":"

Sorry, this entry is only available in Portugu\u00eas do Brasil<\/a>.<\/p>","protected":false},"featured_media":2928,"template":"","cat_especialidades":[],"publicacoes-professores":[115],"class_list":["post-2926","publicacoes","type-publicacoes","status-publish","has-post-thumbnail","hentry","publicacoes-professores-paulo-roberto-falcao-leal"],"acf":[],"yoast_head":"\n(Portugu\u00eas do Brasil) Efficacy of Standard Triple Therapy for Helicobacter pylori Eradication and Early Postoperative Complications in Patients Undergoing Roux-en-Y Gastric Bypass - Instituto Carlos Chagas<\/title>\n<meta name=\"description\" content=\"(Portugu\u00eas do Brasil) Authors: Ver\u00f3nica Jessenia Caicedo Romero, Karynne Grutter Lopes, Luiz Guilherme Kraemer-Aguiar and Paulo Roberto Falc\u00e3o Leal. Objective: We aimed to evaluate the efficacy of standard triple therapy (STT) for Helicobacter pylori (HP) eradication and early postoperative complications in patients undergoing Roux-en-Y gastric bypass (RYGB). Methods: This prospective observational study included 543 patients submitted to RYGB (81.6% females, aged = 38 \u2013 9 years, body mass index = 41.7 [38.4\u201345.4] kg\/m2 ). Before surgery, they collected biopsies through upper gastrointestinal endoscopy (UGE), which were HP-positive or HP-negative. STT-treated HP-positive patients who collected intraoperative gastric mucosa specimens. These patients were reclassified according to HP-eradication or HPnoneffective through histological analysis. All patients were followed up for 30 days after surgery to assess complications. Results: Before surgery, 36.4% of patients were HP-positive, and the first-line STT was effective at 90.9%. No differences between groups were detected for clinical complications and UGE data, except for the percentage of endoscopy and dilations, predominantly occurring in the HP-negative group. Symptoms of gastrointestinal bleeding and stenosis were reported, respectively, in 2% and 6.4% of HP-negative patients, with no difference between groups. No patient of the HP-positive group underwent endoscopic dilation. No postoperative clinical complications were noticed in the HP-noneffective group. Conclusions: Before surgery, STT effectively eradicated HP infection in most treated patients, but HP persistence did not influence complications or mortality during 30 days after surgery. Keywords: obesity, bariatric surgery, Helicobacter pylori infection, morbidity, mortality\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.carloschagas.org.br\/en\/publicacoes\/efficacy-of-standard-triple-therapy-for-helicobacter-pylori-eradication-and-early-postoperative-complications-in-patients-undergoing-roux-en-y-gastric-bypass\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"(Portugu\u00eas do Brasil) Efficacy of Standard Triple Therapy for Helicobacter pylori Eradication and Early Postoperative Complications in Patients Undergoing Roux-en-Y Gastric Bypass - Instituto Carlos Chagas\" \/>\n<meta property=\"og:description\" content=\"Sorry, this entry is only available in Portugu\u00eas do Brasil.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.carloschagas.org.br\/en\/publicacoes\/efficacy-of-standard-triple-therapy-for-helicobacter-pylori-eradication-and-early-postoperative-complications-in-patients-undergoing-roux-en-y-gastric-bypass\/\" \/>\n<meta property=\"og:site_name\" content=\"Instituto Carlos Chagas\" \/>\n<meta property=\"article:modified_time\" content=\"2025-01-27T14:23:29+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.carloschagas.org.br\/wp-content\/uploads\/2025\/01\/romero-et-al-2024-efficacy-of-standard-triple-therapy-for-helicobacter-pylori-eradication-and-early-postoperative1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"812\" \/>\n\t<meta property=\"og:image:height\" content=\"539\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.carloschagas.org.br\\\/en\\\/publicacoes\\\/efficacy-of-standard-triple-therapy-for-helicobacter-pylori-eradication-and-early-postoperative-complications-in-patients-undergoing-roux-en-y-gastric-bypass\\\/\",\"url\":\"https:\\\/\\\/www.carloschagas.org.br\\\/en\\\/publicacoes\\\/efficacy-of-standard-triple-therapy-for-helicobacter-pylori-eradication-and-early-postoperative-complications-in-patients-undergoing-roux-en-y-gastric-bypass\\\/\",\"name\":\"(Portugu\u00eas do Brasil) Efficacy of Standard Triple Therapy for Helicobacter pylori Eradication and Early Postoperative Complications in Patients Undergoing Roux-en-Y Gastric Bypass - 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Objective: We aimed to evaluate the efficacy of standard triple therapy (STT) for Helicobacter pylori (HP) eradication and early postoperative complications in patients undergoing Roux-en-Y gastric bypass (RYGB). Methods: This prospective observational study included 543 patients submitted to RYGB (81.6% females, aged = 38 \u2013 9 years, body mass index = 41.7 [38.4\u201345.4] kg\/m2 ). Before surgery, they collected biopsies through upper gastrointestinal endoscopy (UGE), which were HP-positive or HP-negative. STT-treated HP-positive patients who collected intraoperative gastric mucosa specimens. These patients were reclassified according to HP-eradication or HPnoneffective through histological analysis. All patients were followed up for 30 days after surgery to assess complications. Results: Before surgery, 36.4% of patients were HP-positive, and the first-line STT was effective at 90.9%. No differences between groups were detected for clinical complications and UGE data, except for the percentage of endoscopy and dilations, predominantly occurring in the HP-negative group. Symptoms of gastrointestinal bleeding and stenosis were reported, respectively, in 2% and 6.4% of HP-negative patients, with no difference between groups. No patient of the HP-positive group underwent endoscopic dilation. No postoperative clinical complications were noticed in the HP-noneffective group. Conclusions: Before surgery, STT effectively eradicated HP infection in most treated patients, but HP persistence did not influence complications or mortality during 30 days after surgery. 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